Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
Yan Chen1, Yao Lu1, Robert J Lee2, Guangya Xiang 1
1School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2 Division of Pharmaceutics and Pharmacology, The Ohio State University, Columbus, OH, USA
Abstract
Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano
encapsulated curcumin and its potential for biomedical applications
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Keywords
curcumin, nanoformulations, bioavailability, nanoparticles, therapy
