A Natural Sulfated Polysaccharide, Calcium Spirulan, Isolated from Spirulina platensis: In Vitra and ex Vivo Evaluation of Anti-Herpes Simplex Virus and Anti-Human Immunodeficiency Virus · Activities
KYOKO HAYASHI. 1 TOSHIMITSU HAYASHI,2 and ICHIRO KOJIMA3
ABSTRACT
A sulfated polysaccharide named calcium spirulan (Ca-SP) has been isolated from a sea alga, Spirulina platensis, as an antiviral component. The anti-human immunodeficiency virus type 1 (HIV-1) and anti-herpes simplex virus type 1 (HSV-1) activities of Ca-SP were compared with those of dextran sulfate (DS) as a representative sulfated polysaccharide. (…)
